WWOX anticorps (N-Term)

N° du produit ABIN7466029

L’anticorps Lapin Polyclonal anti-WWOX a été validé pour WB. Il convient pour détecter WWOX dans des échantillons de Humain.

Aperçu rapide pour WWOX anticorps (N-Term) (ABIN7466029)

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WWOX anticorps

Épitope: N-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human WWOX. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.38 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WW domain containing oxidoreductase

Sujet: WW domain containing oxidoreductase , D16S432E , EIEE28 , FOR , FRA16D , HHCMA56 , PRO0128 , SCAR12 , SDR41C1 , WOX1,WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq]

Poids moléculaire: 47 kDa

ID gène: 51741

UniProt: Q9NZC7